Physical biology of chromatin

at LBMC, CNRS, ENS Lyon, University of Lyon

In close connection with experimental biology, our research addresses generic or specific biological

questions on chromatin and gene regulation by developing physical and computational models.

Particularly, we focus on the spatio-temporal dynamics of eukaryotic chromosomes. Our research

tackles important questions regarding the coupling between 3D structure and functions of

chromatin. Our objective is to provide some universal principles driving chromatin folding and regulation, while contextualizing our approaches to fundamental, specific

problems of 3D genomics.