Last update: 22.04.2009
Release Information:
UNIO’08
Version 1.0.4, April 15, 2009
Copyright © 2002-2008 Torsten Herrmann
(Previous release: UNIO Version 1.0.3, April 9, 2009.)
(Previous release: UNIO Version 1.0.2, February 6, 2009.)
(Previous release: UNIO Version 1.0.1, January 13, 2009.)
(First release: UNIO Version 1.0.0, December 11, 2008.)
Contact:
Dr. Torsten Herrmann
Centre Européen de RMN à Très Hauts Champs
Université de Lyon/FRE 3008 CNRS / ENS Lyon
5 rue de la Doua
69100 Villeurbanne, France
Email: torsten.herrmann@ens-lyon.fr
UNIO’08
UNIO enables you to perform automated NMR data analysis for protein 3D structure determination. UNIO NMR data analysis interconnects the MATCH algorithm for backbone assignment (1), the ASCAN algorithm for side-chain assignment (2) and the CANDID algorithm for NOE assignment (3). The ATNOS algorithm for robust signal identification in NMR spectra is employed to grant each of the three expert-systems direct access to the raw NMR data (4), thus enabling integrated and consistent data evaluation. The UNIO data analysis protocol requires only a minimal set of 3-6 NMR spectra, namely APSY and NOESY, and features high computational efficiency. The experience gained so far shows that the UNIO approach leads to objective and consistent NMR data interpretation (see UNIO structures).
(1) Volk, J.; Herrmann, T.; Wüthrich, K. J. Biomol.NMR. 2008, 41, 127-138.
(2) Fiorito, F.; Damberger, F.F.; Herrmann, T.; Wüthrich, K. J. Biomol. NMR 2008, 42, 23-33.
(3) Herrmann, T.; Güntert, P.; Wüthrich, K. J. Mol. Biol. 2002, 319, 209-227.
(4) Herrmann, T.; Güntert, P.; Wüthrich, K. J. Biomol. NMR 2002, 24, 171-189.
UNIO’08 User’s Guide:
Download the latest version of the User’s Guide for UNIO in PDF format: Unio-UserGuide.pdf [11.8MB]. (Using Acrobat Reader or Mac Preview)
(Last update: Dec 11, 2008)
UNIO’08 License:
Unio is free-of-charge for academic users. Please request a license via email along with information about your institution and PI.
