Torsten HERRMANN, Ph.D.

Research director CNRS

Université de Lyon, Institut des Sciences Analytiques

Centre de RMN à Très Hauts Champs de Lyon (CRMN)

(UMR 5280 CNRS / ENS Lyon / UCB Lyon 1)

5 rue de la Doua

69100 Villeurbanne, France

Phone: +33 - 4 26 23 3882

Web:  http://perso.ens.lyon.fr/torsten.herrmann/

Email: torsten.herrmann@ens-lyon.fr

Our research interest is in Nuclear Magnetic Resonance (solution and solid-state NMR) experiment-driven modeling of biological macromolecules and protein assemblies.

The research focuses on the development of mathematical, physical and biochemical models for analyzing, solving and understanding problems concerning the accurate and objective interpretation of NMR spectra acquired for biological macromolecular systems.

The research objectives aim at providing the most direct link possible between multi-dimensional NMR spectroscopy (NMR only provides indirect biomolecular fingerprints) and three-dimensional protein structure and dynamics in order to obtain an accurate, efficient and reproducible structural and functional description of biological macromolecules or macromolecular complexes at atomic and time-resolved resolution.

Over more than a decade of innovative research we have developed unsupervised, sophisticated computational data analysis models and protocols for NMR experiment-driven molecular modeling (see Research: UNIO, MATCH, ASCAN, ATNOS and CANDID) that have been successfully applied in thousands of NMR structure determination projects (approx. 20% of all NMR structures determined). Academic and industrial software licenses have been distributed to and are presently used in more than 750 NMR research laboratories and structural biology centers world-wide.

We are always looking for talented Master students, Ph.D. students and Post doctoral fellows. If you are interested in joining our research, then please send your CV to torsten.herrmann@ens-lyon.fr.